Apraketo- 200mg

Apraketo- 200 mg

Composition: Ketoconazole 200mg

Therapeutic class: Antifungal

What is Apraketo- 200?

It is an antifungal medicine used to treat fungal or yeast infections.

Uses of Apraketo-200

It is for severe systemic fungal infections

How does Apraketo work?

Ketoconazole works by -

• Blocking ergosterol synthesis

• Which breaks the fungal cell membrane integrity

• Causes fungal cell death.

Common Side-effects

• Skin rashes

• Irregular heartbeats

• Abdominal pain

• Loss of appetite

• Dark urine

• Fatigue

• Diarrhea

Serious Side Effects

• These are dose-dependent side effects that occur at high doses or long-term use

• Severe liver toxicity –jaundice, pale urine, and stool

• Adrenal insufficiency

• Arrhythmia

• QT prolongation

Contraindications

Not to be used in patients –

• Hypersensitive or allergic to the drug or its excipients.

• Breastfeeding mothers

• Pregnant women

Precautions

It should be used cautiously in patients with

• Adrenal problems

• Alcohol abuse

• History of irregular heartbeat

• Liver disease

• Hypoachlorhyrda

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

Regular monitoring of the liver function, cardiac rhythms, and adrenal functions.

General Instructions

• Do not skip doses

• Take after food, at the same time

Drug Interactions

Ketoconazole should be used with extreme caution with

Anti-cholesterol drugs, anticoagulants, cardiovascular drugs, immunosuppressants, HIV, or antipsychotics.