Cytarzer 1000mg

Cytarzer 1000mg

Composition:  Cytarabine 1000mg

Classification: Anticancer Medicine

What is Cytarzer?

It is an anticancer medicine used in various types of blood cancers and solid tumors.

Uses of Cytarzer

• Advanced stage Acute Myeloid Leukemia (AML).

• Leukemia of the meninges

• Lymphocytic/ No lymphocytic leukemia

• Refractory leukemia

How does it work?

It mimics DNA bases, inhibits DNA replication, and terminates the chain, causing cell death.

Common side effects

• Hair loss

• Skin rashes

• Liver dysfunctions

• Mouth sores

• Weakness

• Indigestion

• Anemia

• Neutropenia

Serious Side Effects

• Dose-dependent side effects –fever, pain, muscle pain

• Neurological dysfunction –confusion, blurring of speech

• Pulmonary embolism and fibrosis

• Irritation of the eye, conjunctivitis.

• Bleeding risk

• Liver toxicity

Precautions

To be used cautiously in patients with –

• Liver dysfunction

• Renal dysfunction

• Immune-compromised patients

• Neurological disorders

Contraindications

• Not to be used if any previous allergy or hypersensitivity to Cytarabine or any excipients.

• Breastfeeding mothers

• Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Monitor blood count and hepatic and neurological assessments regularly, manage infection risks, and assess ocular and renal functions.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

• To be administered intrathecal, subcutaneous, or as a slow IV infusion.

• To be used immediately after reconstitution.