Dasakast 70mg Tablet

Dasakast 70 MG Tablet

Composition—Dasatanib 70mg IP

Therapeutic class: Antineoplastic

What is Dasakast?

Dasakast is an anticancer drug and is used in targeted therapy for both chronic and acute leukemia.

It is used for Philadelphia chromosome-positive leukemia when no other drug works.

Uses of Dasakast

• Myeloid Leukemia (Chronic)

• Lymphocytic leukemia (Acute)

How does Dasakast work?

It inhibits the cancer cell enzyme (tyrosine kinase)

Stops cancer cell growth and multiplication

Shrink cancer

Common Side Effects

• Infections- cough, changing temperatures, headache, chills, and fever.

• Bleeding of gums and nose—fall in blood count

• Hemorrhage

• Diarrhea

• Skin rashes, dryness, and itching

• Oedema

• Fatigue

• Stomach bloating and pain

Severe Side Effects

• Scarring of the lungs

• Bleeding in the gastrointestinal tract

• A severe skin reaction

• QT Prolongation—irregular heartbeats

Contraindications

• Not to be used in patients

• Hypersensitivity or allergic reaction to the drug or its excipients.

• Breastfeeding mothers—it may be passed on to infants or breastfeeding children

• Pregnant women—it may be teratogenic.

Toxicities

• Bone marrow suppression—low blood count

• Pleural effusion—shortness of breath, fluid buildup around the lungs

• Hematological toxicity—bleeding risk, decreased platelet count

• Hepatotoxicity—elevated enzymes

• Cardiovascular Toxicity—irregular heartbeat

Precautions

To be used cautiously in patients with

• Hepatic impaired functions

• Renal impaired functions

• Blood disorders

• Cardiovascular disorders

Warnings

Prescription drug to be used under medical supervision

Important Safety and Monitoring Information

Dasakast requires regular monitoring for hematological functions, blood pressure, liver functions, ECG, regular monitoring of electrolytes.