Instgra 30 Tab/90 Tab

Instgra 30 Tab/90 Tab

The Instgra (Dolutegravir 50 mg) is a medicine taken orally for patients who have HIV (Human immunodeficiency virus). The patients are generally adults, adolescents, and children above the age of six. The Instgra drug contains dolutegravir, which belongs to anti-retrioviral medicines called integrase inhibitors (INIs). HIV attacks the body's immune system and can be transmitted through contaminated blood, semen, and vaginal fluid. This anti-HIV drug helps increase a type of white blood cell, called CD4, to help fight the infection. It works by inhibiting the HIV integrase, which blocks the strand transfer step of the retroviral DNA, a crucial step in HIV production within the body. Thus, it stops the viral activity. The Instgra 50mg is given to the patients with other anti-retrioviral medicines in combination therapy. The Instgra (Dolutegravir 50 mg) is given to those patients infected with human immunodeficiency virus (HIV).

Administration of Instgra (Dolutegravir 50 mg):

This medicine is taken orally with or without the meals. Do not crush or chew the tablet. Take it with a glass of water and swallow it. Since this medicine is not to be taken without a prescription from the doctor, it is better to buy it after getting consultation from a professional physician. Discuss with the doctor about the symptoms first.

When should the Instgra (Dolutegravir 50 mg) be avoided or taken cautiously?

- If the patient is pregnant or breastfeeding.

- If the patient has a job that involves operating machines or driving. This is dangerous because the medicine can cause dizziness after taking.

- Discuss with the doctor beforehand if the person has any allergic reaction to the ingredients of the medicine. If the patient has an allergic reaction after starting the medication, then talk to the doctor immediately.

- If the patient has a medical history of kidney problems or takes medicines regarding the kidney.

- If the patient has a medical history of liver problems or surgery and is on the medication for the same. It is advisable to consult a doctor and discuss the prescriptions and non-prescriptions before taking up this medicine.

- If the patient has been prescribed the Instgra (Dolutegravir 50 mg), it is better to stop the alcohol consumption.

- If the patient has a prescription that contains medicine for epilepsy, diabetes, TB, heartburn, and herbal medicine like st John’s wort for depression.

What are the most common types of side effects of Instgra (Dolutegravir 50 mg)?

- Nausea and vomiting

- Diarrhea

- Light-headedness and dizziness

- Rash and itching on the skin

- Lack of energy or fatigue

- Insomnia

- Depression

- Increase in liver enzymes in the body.

What are the uncommon types of side effects of Instgra (Dolutegravir 50 mg)?

- Liver failure.

Although these side effects are not very severe and subside with time, it is better to visit the doctor if the effects become severe. Things like liver failure can be lethal on the body, so go to the doctor and consult them. Do not stop abruptly or discontinue the medication, as that can cause unwanted consequences like the rapid increase of the virus in the body. Take medicine for as long as the physician has prescribed it. Also, do not take up more than the prescribed dose in case of a missed dose. This can lead to overdosing – further risking the patient's health and creating unwanted consequences as well. If missed, take it at the next interval as much as it has been asked to.

Note: These are not all possible side-effects of Instgra 50 mg, please ask your doctor for more information regarding the same.