Zoldokast

Zoldokast –

Composition: Zolderonic acid IP- 4mg

Classification: Bisphosphonates

What is Zoldokast?

Cancer treatment often causes bone loss, it is widely used to treat cancer-related bone complications and osteoporosis.

Uses of Zoldokast

• Osteoporosis

• High calcium levels caused by malignancies

• Secondary cancers in the bone

• Chronic bone disorder

• Bone marrow cancers

• Bone lesions

How does Zoldokast work?

• Osteoclast causes bone dissolution.

• Inhibiting osteoclasts stops bone dissolution, preventing bone integrity.

Common Side Effects

• Diarrhea

• Loss of appetite

• Bone, muscle pain

• Nausea

• Vomiting

• Fluid retention

• Dizziness

• Dryness of the skin

Serious side effects

• Lowered calcium levels – tingling in fingers

• Kidney failure

• Irregular heartbeat

• Bone fractures

• Osteonecrosis of the jawbone

• Eye inflammation

• Blood in urine

• Dizziness, confusion

• Shortness of breath

• Rapid weight gain

• Decreased vision

Precautions:

To be used cautiously in

• Kidney disorders

• Any dental procedures

• Respiratory disorder

• Elderly

• Thyroid disorder

• Cardiovascular disease

• Vitamin D levels or low calcium levels

Contraindications

• Not to be used if any previous allergy or hypersensitivity to Zolderonic acid or any excipients.

• Breastfeeding mothers

• Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Regular monitor –

• Kidney functions

• Liver functions

• Cardiac functions

• Renal functions

• Respiratory functions

Administration Instructions

• To be administered as a slow IV infusion only.

• Do not give as an IV push/bolus.

• To be used immediately after reconstitution.

• Ensure patient hydration before infusion.

• Do not mix with calcium-containing IV solutions.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.