Bortezomib
Bortezomib
Classification: Anticancer medicine
What is Bortezomib?
It is an anticancer medicine for IV or Subcutaneous administration.
Uses of Bortezomib
- Newly diagnosed with myeloma
- Relapsed myeloma
- Mantle cell lymphoma
How does it work?
- It inhibits the repair mechanisms
- Causes the accumulation of toxic proteins
- Disrupts DNA signaling
- Causes cancer cell death
Common Side Effects
- Tiredness
- Reduced appetite
- Neuropathy
- Fever
- Skin rashes
- Dizziness
- Insomnia
- Headache
- Delays wound healing
Serious Side Effects
- Bone marrow suppression
- Respiratory distress
- Risk of severe infections
- Severe bleeding
- Hepatic toxicity
- Low blood pressure
- Heart complications – arrhythmia
- Severely low blood pressure
- Electrolyte imbalance
Precautions
To be used cautiously in
- Elderly patients
- Neuropathic condition
- Cardiovascular disease
- Low blood pressure
- Immune-compromised individuals
- Ongoing surgery
- Liver disorders
Contraindications
Not to be used in patients-
- Hypersensitivity or allergy to the drug composition
- Pregnant and breastfeeding
- Severe liver disorders
- Active infections
Warnings
Prescription drug to be used under medical supervision.
Important safety and monitoring information
- Kidney functions
- Liver functions
- Total blood count
- Early signs of neuropathy
- Blood pressure
- Infections
- Hydration
- Neurological symptoms – anxiety, confusion
- Chest pain
Storage
To be stored at 2-8 degrees Celsius.
To be protected from light.
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Formulations based on "Bortezomib" (3)
Bortecad 2.5mg Injection
Bortezomib (2.5mg)
Multiple myeloma and mantle-cell lymphoma are both treated by Bortecad 2.5mg Injection. It demonstrates its efficacy by halting or reducing the proliferation of cancer cells.
Proteoz 2.5mg Injection
Bortezomib (2.5mg)
Multiple myeloma and mantle-cell lymphoma are both treated by Proteoz 2.5mg Injection. It demonstrates its efficacy by halting or reducing the proliferation of cancer cells.
Borviz 2.5mg Injection
Bortezomib (2.5mg)
Multiple myeloma and mantle-cell lymphoma are both treated by Borviz 2.5mg Injection. It demonstrates its efficacy by halting or reducing the proliferation of cancer cells.