Calcium Leucovorin 15mg

Calcium Leucovorin 15mg

Classification: Folic acid Derivative

What is calcium leucovorin injection?

It is used as an adjuvant cancer care treatment to –

• Reduce the toxicity
• Side effects of chemotherapy
• Enhance chemotherapy efficacy

Uses of leucovorin

• Colorectal cancer (adjuvant to 5-fluorouracil)
• Rescue therapy after methotrexate, trimethoprim and methotrexate therapy
• Adjuvant to anti-folate agents in blood cancer, lymphomas, solid tumors, etc.

How does it work?

• Recovering folate levels in anti-folate cancer therapies
• Enhanced the chemotherapy effects

Common side effects

• Nausea
• Tiredness
• Skin rashes/mouth sores
• GIT upset

Serious side effects

• Neurological conditions - seizures
• Anaphylactic reaction – swelling of lips, face, tongue etc.
• Severe gastrointestinal side effects

Contraindications

• Not to be used if any previous allergy or hypersensitivity to leucovorin or any excipients
• Low RBC count
• Breastfeeding mothers
• Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities. Not to be used as a folate supplement.

Important safety and monitoring information

• Regularly monitor blood count
• Hepatic and neurological assessments
• Manage infection risks
• Assess ocular and renal functions

Storage

To be stored in the refrigerator-

At 2–8 degrees Celsius. Protected from light.

Administration Instructions

• To be administered IV and IM
• To be used immediately after reconstitution

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