Nintedanib

Nintedanib

Classification: Anticancer and Anti-fibrotic

Nintedanib is an oncology medicine that has anti-fibrotic properties and is widely used for various diseases of the lungs and cancers.

Uses:

• • Non-small cell lung cancer
• • Pulmonary fibrosis
• • Systemic sclerosis of the lungs

Working of Nintedanib –

• • It inhibits growth factors
• • It inhibits angiogenesis and fibrosis

Common Side Effects

• • Diarrhea
• • Nausea
• • Vomiting
• • Liver dysfunction
• • Decreased weight
• • Reduced appetite
• • Headache
• • Tiredness

Serious Side Effects

• • Gastrointestinal bleeding
• • Liver toxicity
• • Thromboembolic events
• • High blood pressure
• • Delayed wound healing
• • GIT perforation

Precautions

To be cautiously used in:

• • Severe liver disorders
• • Bleeding disorders
• • Heart disorders
• • Elderly patients
• • Gastrointestinal disorders
• • Before and after surgery

Contraindications

• • Allergy or hypersensitivity to drug components
• • Breastfeeding mothers
• • Pregnant women

Warning

To be used under medical prescription only.

Safety and Monitoring Information

• • Monitor –liver functions, cardiac functions, blood pressure, total blood count
• • Women must use effective contraception while using the medication and for 3 months after the usage.

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