Pirfenidone
Pirfenidone
Classification: Respiratory Medicine
What is Pirfenidone?
It is an antifibrotic drug used against scarring of the lung tissues.
Uses
- • Pulmonary Fibrosis
- • Liver fibrosis
- • Systemic sclerosis
Working of Pirfenidone
- • It reduces inflammation and prevents lung scars.
Benefits
- • It’s well tolerated
- • Slows down lung scarring
- • Delays disease progression
- • Preserves Lung capacity
Common Side Effects
- • Nausea
- • Diarrhea
- • Skin rashes due to photosensitivity
Serious Side Effects
- • Severe hepatic dysfunction
- • Jaundice
- • Gastric bleeding
- • Tiredness
- • Blistering or peeling of skin
Precautions
To be used cautiously in patients with –
- • Liver disorders
- • Renal disorders
- • Elderly patients
- • Pre-existing skin infections
- • Smoking
- • Alcohol
- • Gastrointestinal disorders
Contraindications
- • Severe Liver dysfunction
- • Severe renal impairment
- • Allergy to drug components
Warnings
To be used as prescribed by the doctor.
Important safety and monitoring information
Regularly monitor –
- • Total blood count
- • Liver functions
- • Infection risks
- • Heart functions
- • Neuropathy
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Formulations based on "Pirfenidone" (2)
Pirfenex 200 mg Tablet
Pirfenidone
Pirfenidone (Pirfenex 200mg) tablet contains an active ingredient called pirfenidone, which is used to treat a lung disease called IPF, which stands for Idiopathic Pulmonary Fibrosis. Pirfenidone (...
Pirfekast 200 Tablet
Pirfenidone
The Pirfekast 200 (Pirfenidone) is an oral drug for adults suffering from mild to moderate idiopathic pulmonary fibrosis, a disease where the tissues in the lung get swelled and scarred – leading t...