Sofosbuvir+Velpatasvir

Sofosbuvir + Velpatasvir

Classification – Hepatitis C Medicine

Sofosbuvir + Velpatasvir combination?

It is a fixed-dose antiviral combination used for Chronic Hepatitis C. It is effective against all major 6 genotypes.

Uses of Sofosbuvir + Velpatasvir combination

• • Chronic Hepatitis C
• • HCV-HIV co-infections
• • Naïve Hepatitis C treatment or /relapsed treatment

Working of Sofosbuvir + Velpatasvir

It mimics natural nucleosides and inhibits RNA replication and multiplication.

Benefits

• • Pan genotypic coverage (effective against all Hepatitis C strains)
• • Shorter treatment duration
• • Can be used in HIV co-infections
• • Can be used with ribavirin
• • Effective in advanced liver diseases
• • In children > 3 years
• • Post liver transplant
• • Low resistance risk

Common Side Effects

Nausea, dizziness, headache, digestive issues, tiredness, diarrhea

Serious Side Effects

• • Severe Bradycardia (when taken with amiodarone)
• • Causes Hepatitis B reactivation
• • Severe liver failure
• • Severe anemia upon use with ribavirin
• • Depression, mood swings, and confusion

Precautions

To be used cautiously in patients

• • Kidney disorders
• • Liver disorder
• • Heart disorders
• • Hepatitis B co-infections – cause reactivation
• • HIV co-infection
• • When used with ribavirin and amiodarone

Contraindications

• • Hypersensitive reaction to drug components
• • Breastfeeding and Pregnant Women

Warning

To be used when prescribed by a medical practitioner.

Not to be used alone for HCV infections.

Important Safety and Monitoring Information

• • Regular monitoring of hepatic functions
• • Renal functions
• • Cardiac functions
• • Co-infections
• • Neuropsychiatric adverse reactions

Drug Interactions

• • Ribavirin and Amiodarone
• • Anticonvulsant
• • Antivirals
• • Cardiovascular medicines
• • Hypertension medicines
• • Antacids and PPIs

Gandhi Medicos – Trusted Hepatitis C Medicines

Gandhi Medicos is a specialty care pharmacy trusted worldwide by leading hospitals, healthcare professionals, and clinicians offering affordable genuine medicines.

✅ Why Choose Gandhi Medicos?

• • 25,000+ satisfied global customers
• • Choice of preference by leading doctors and hospitals
• • Delivering to over 50+ countries
• • WHO-GMP-certified medicines
• • Extensive Portfolio – including HIV, Hepatitis, and Transplant Therapy

What Sets Gandhi Medicos Apart?

• • Reliable distribution of branded & generic Hepatitis B and C medicines
• • Temperature-controlled shipment
• • Timely response and strong customer support
• • Collaboration with leading pharmaceutical partners